| Issue |
Math. Model. Nat. Phenom.
Volume 1, Number 2, 2006
Hematopoiesis and blood diseases
|
|
|---|---|---|
| Page(s) | 45 - 69 | |
| DOI | https://doi.org/10.1051/mmnp:2008004 | |
| Published online | 15 May 2008 | |
Observations on the Pathophysiology and Mechanisms for Cyclic Neutropenia
1
Department of Engineering Mathematics, University
of Bristol, Bristol, UK, BS8 1TR
2
Department of Medicine, University of Washington, Seattle,
Washington, USA, 98195
3
Department of Mathematics and Centre for
Nonlinear Dynamics, McGill University 3655 Promenade Sir William Osler,
Montreal, QC, Canada, H3G 1Y6
Corresponding author: michael.mackey@mcgill.ca
We review the basic pathology of cyclical neutropenia in both humans and the grey collie, and examine the role that mathematical modeling of hematopoietic cell production has played in our understanding of the origins of this fascinating dynamical disease.
Mathematics Subject Classification: 92C50
Key words: cyclic neutropenia
© EDP Sciences, 2006
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