Math. Model. Nat. Phenom.
Volume 5, Number 3, 2010Mathematical modeling in the medical sciences
|28 - 39
|28 April 2010
The Effect of Bacteria on Epidermal Wound Healing
School of Mathematical Sciences, Rochester Institute of Technology
* Corresponding author. E-mail:
Epidermal wound healing is a complex process that repairs injured tissue. The complexity of this process increases when bacteria are present in a wound; the bacteria interaction determines whether infection sets in. Because of underlying physiological problems infected wounds do not follow the normal healing pattern. In this paper we present a mathematical model of the healing of both infected and uninfected wounds. At the core of our model is an account of the initiation of angiogenesis by macrophage-derived growth factors. We express the model as a system of reaction-diffusion equations, and we present results of computations for a version of the model with one spatial dimension.
Mathematics Subject Classification: 92B05 / 92C17 / 92C30 / 92C37
Key words: wound healing / angiogenesis / growth factors / bacteria infection
© EDP Sciences, 2010
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