Math. Model. Nat. Phenom.
Volume 5, Number 3, 2010Mathematical modeling in the medical sciences
|Page(s)||28 - 39|
|Published online||28 April 2010|
The Effect of Bacteria on Epidermal Wound Healing
School of Mathematical Sciences, Rochester Institute of Technology
* Corresponding author. E-mail:
Epidermal wound healing is a complex process that repairs injured tissue. The complexity of this process increases when bacteria are present in a wound; the bacteria interaction determines whether infection sets in. Because of underlying physiological problems infected wounds do not follow the normal healing pattern. In this paper we present a mathematical model of the healing of both infected and uninfected wounds. At the core of our model is an account of the initiation of angiogenesis by macrophage-derived growth factors. We express the model as a system of reaction-diffusion equations, and we present results of computations for a version of the model with one spatial dimension.
Mathematics Subject Classification: 92B05 / 92C17 / 92C30 / 92C37
Key words: wound healing / angiogenesis / growth factors / bacteria infection
© EDP Sciences, 2010
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.