Math. Model. Nat. Phenom.
Volume 10, Number 1, 2015Hybrid models
|Page(s)||36 - 47|
|Published online||12 December 2014|
Influence of Fibrinogen Deficiency on Clot Formation in Flow by Hybrid Model
1 Institut Camille Jordan, UMR 5208
CNRS, University Lyon 1, 69622
2 INRIA Team Dracula, INRIA Antenne Lyon la Doua, 69603 Villeurbanne, France
3 Institute of Mechanical Engineering Problems, 199178 Saint Petersburg, Russia
Corresponding author. E-mail: firstname.lastname@example.org
In this work we develop the 2D model suggested in  in order to study the impact of fibrinogen concentration and the fibrin polymer production rate on clot growth in flow. The model is based on the method of Dissipative Particle Dynamics describing blood plasma flow and platelet suspension and on a system of partial differential equations describing blood coagulation regulatory network. We study the influence of parameters on clot development and on its final size.
Mathematics Subject Classification: 74F10 / 92C35 / 92C50
Key words: blood coagulation / clot growth / hybrid models / Dissipative Particle Dynamics
© EDP Sciences, 2015
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