| Issue |
Math. Model. Nat. Phenom.
Volume 10, Number 1, 2015
Hybrid models
|
|
|---|---|---|
| Page(s) | 36 - 47 | |
| DOI | https://doi.org/10.1051/mmnp/201510102 | |
| Published online | 12 December 2014 | |
Influence of Fibrinogen Deficiency on Clot Formation in Flow by Hybrid Model
1 Institut Camille Jordan, UMR 5208
CNRS, University Lyon 1, 69622
Villeurbanne,
France
2 INRIA Team Dracula, INRIA Antenne
Lyon la Doua, 69603
Villeurbanne,
France
3 Institute of Mechanical Engineering
Problems, 199178
Saint Petersburg,
Russia
⋆
Corresponding author. E-mail: tosenberger@math.univ-lyon1.fr
In this work we develop the 2D model suggested in [32] in order to study the impact of fibrinogen concentration and the fibrin polymer production rate on clot growth in flow. The model is based on the method of Dissipative Particle Dynamics describing blood plasma flow and platelet suspension and on a system of partial differential equations describing blood coagulation regulatory network. We study the influence of parameters on clot development and on its final size.
Mathematics Subject Classification: 74F10 / 92C35 / 92C50
Key words: blood coagulation / clot growth / hybrid models / Dissipative Particle Dynamics
© EDP Sciences, 2015
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