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All issues Volume 9 / No 3 (2014) Math. Model. Nat. Phenom., 9 3 (2014) 107-123 References
Free Access
Issue
Math. Model. Nat. Phenom.
Volume 9, Number 3, 2014
Biological evolution
Page(s) 107 - 123
DOI https://doi.org/10.1051/mmnp/20149307
Published online 28 May 2014
  1. S.S. Apte, M.G. Mattei, B.R. Olsen. Mapping of the human BAX gene to chromosome 19q13.3-q13.4 and isolation of a novel alternatively spliced transcript, BAX delta. Genomics, 26 (1995), 592-594. [CrossRef] [PubMed] [Google Scholar]
  2. C.J. Bakkenist, M.B. Kastan. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature, 421 (2003), 499-506. [CrossRef] [PubMed] [Google Scholar]
  3. E. Batchelor, C.S. Mock, I. Bhan, A. Loewer, G. Lahav. Recurrent initiation: A mechanism for triggering p53 pulses in response to DNA damage. Molecular Cell, 30 (2008), 277-289. [CrossRef] [PubMed] [Google Scholar]
  4. E. Batchelor, A. Loewer, G. Lahav. The ups and downs of p53: understanding protein dynamics in single cells. Nature Reviews Cancer, 9 (2009), 371-377. [CrossRef] [PubMed] [Google Scholar]
  5. C. Blattner, T. Hay, D.W. Meek, D.P. Lane. Hypophosphorylation of Mdm2 augments p53 stability. Molecular and Cellular Biology, 22 (2002), 6170-6182. [CrossRef] [PubMed] [Google Scholar]
  6. A.M. Bode, Z. Dong. Post-translational modifications of p53 in tumorigenesis. Nat. Rev. Cancer, 4 (2004), 793-805. [CrossRef] [PubMed] [Google Scholar]
  7. A. Cangiani, R. Natalini. A spatial model of cellular molecular trafficking including active transport along microtubules. J. Theor. Biol., 267 (2010), 614-625. [CrossRef] [PubMed] [Google Scholar]
  8. A. Carracedo, A. Alimonti, P.P. Pandolfi. PTEN level in tumor suppression: how much is too little? Cancer Research, 71 (2011), 629-633. [CrossRef] [PubMed] [Google Scholar]
  9. C.H. Chung, K. Ely, L. McGavran, M. Varella-Garcia, J. Parker, N. Parker, C. Jarrett, J. Carter, B.A. Murphy, J. Netterville, B.B. Burkey, R. Sinard, A. Cmelak, S. Levy, W.G. Yarbrough, R.J. Slebos, F.R. Hirsch. Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas. J. Clin. Oncol., 24 (2006), 4170-4176. [CrossRef] [PubMed] [Google Scholar]
  10. A. Ciliberto, B. Novak, J. Tyson. Steady states and oscillations in the p53/Mdm2 network. Cell Cycle, 4:3 (2005), 488-493. [CrossRef] [PubMed] [Google Scholar]
  11. S.E. Coupland, N. Bechrakis, A. Schuler, I. Anagnostopoulos, M. Hummel, N. Bornfeld, H. Stein. Expression patterns of cyclin D1 and related proteins regulating G1-S phase transition in uveal melanoma and retinoblastoma. Br. J. Ophthalmol., 82 (1998), 961-970. [CrossRef] [PubMed] [Google Scholar]
  12. L. Dimitrio, J. Clairambault, R. Natalini. A spatial physiological model for p53 intracellular dynamics. J. Theor. Biol., 316 (2012), 9-24. [Google Scholar]
  13. N. Geva-Zatorsky, N. Rosenfeld, S. Itzkovitz, R. Milo, A. Sigal, E. Dekel, T. Yarnitzky, Y. Liron, P. Polak, G. Lahav, U. Alon. Oscillations and variability in the p53 system. Mol. Sys. Biol., 2 (2006), 0033. [Google Scholar]
  14. P. Giannakakou, D.L. Sackett, Y. Ward, K.R. Webster, M.V. Blagosklonny, T. Fojo. p53 is associated with cellular microtubules and is transported to the nucleus by dynein. Nat. Cell Biol., 2 (2000), 709-717. [CrossRef] [PubMed] [Google Scholar]
  15. P. Hikisz, Z.M. Kilianska. Puma, a critical mediator of cell death - one decade on from its discovery. Cell. Mol. Biol. Lett., 17 (2012), 646-669. [CrossRef] [PubMed] [Google Scholar]
  16. K.K. Khanna, M.F. Lavin, S.P. Jackson, T.D. Mulhern. ATM, a central controller of cellular responses to DNA damage. Cell Death Diff., 8 (2001), 1052-1065. [CrossRef] [Google Scholar]
  17. G. Lahav, N. Rosenfield, A. Sigal, N. Geva-Zatorsky, A.J. Levine, M.B. Elowitz, U. Alon. Dynamics of the p53-Mdm2 feedback loop in individual cells. Nat. Gen., 36 (2004), 147-150. [CrossRef] [PubMed] [Google Scholar]
  18. A. Loewer, E. Batchelor, G. Gaglia, G. Lahav. Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells. Cell, 142 (2010), 89-100. [CrossRef] [PubMed] [Google Scholar]
  19. L. Ma, J. Wagner, J.J. Rice, W. Hu, A.J. Levine, G.A. Stolovitzky. A plausible model for the digital response of p53 to DNA damage. Proc. Natl. Acad. Sci. USA, 102 (2005), 14266-14271. [CrossRef] [Google Scholar]
  20. J.J. Manfredi. The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor. Genes & Development, 24 (2010), 1580-1589. [CrossRef] [PubMed] [Google Scholar]
  21. J.C. Marine. p53 stabilization: the importance of nuclear import. Cell Death Diff., 17 (2010), 191-192. [CrossRef] [Google Scholar]
  22. L.D. Mayo, D.B. Donner. A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus. Proc. Natl. Acad. Sci. USA, 98 (2001), 11598-11603. [CrossRef] [Google Scholar]
  23. G.I. Mihalas, M. Neamtu, D. Opris, R.F. Horhat. A dynamic P53-MDM2 model with time delay. Chaos, Solitons and Fractals, 30 (2006), 936-945. [CrossRef] [MathSciNet] [Google Scholar]
  24. N. Monk. Oscillatory expression of Hes1, p53, and NF-кB driven by transcriptional time delays. Curr. Biol., 13 (2003), 1409-1413. [CrossRef] [PubMed] [Google Scholar]
  25. C.C. Morton. Cancer sentry flashes two-tiered warning, http://hms.harvard.edu/news/cancer-sentry-flashes-two-tiered-warning-9-3-10, 2010. [Google Scholar]
  26. H. Offer, M. Milyavsky, N. Erez, D. Matas, I. Zurer, C.C. Harris, V. Rotter. Structural and functional involvement of p53 in BER in vitro and in vivo. Oncogene, 20 (2001), 581-589. [CrossRef] [PubMed] [Google Scholar]
  27. Y. Ogawara, S. Kishishita, T. Obata, Y. Isazawa, T. Suzuki, K. Tanaka, N. Masuyama, Y. Gotoh. Akt enhances Mdm2-mediated ubiquitination and degradation of p53. J. Biol. Chem., 277 (2002), 21843-21850. [CrossRef] [PubMed] [Google Scholar]
  28. D.A. Ouattara, W. Abou-Jaoude, M. Kaufman. From structure to dynamics: Frequency tuning in the p53-Mdm2 network. II Differential and stochastic approaches. J. Theor. Biol., 264 (2010), 1177-1189. [CrossRef] [PubMed] [Google Scholar]
  29. C.J. Proctor, D.A. Gray. Explaining oscillations and variability in the p53-Mdm2 system. BMC Systems Biology, 2 (2008), 1-20. [CrossRef] [PubMed] [Google Scholar]
  30. T. Pu, X.P. Zhang, F. Liu, W. Wang. Coordination of the nuclear and cytoplasmic activities of p53 in response to DNA damage. Biophysical Journal, 99 (2010), 1696-1705. [CrossRef] [PubMed] [Google Scholar]
  31. K. Puszynski, B. Hat, T. Lipniacki. Oscillations and bistability in the stochastic model of p53 regulation. J. Theor. Biol., 254 (2008), 452-465. [CrossRef] [PubMed] [Google Scholar]
  32. K. Puszynski, R. Bertolusso, T. Lipniacki. Crosstalk between p53 and NF-кB systems: pro- and anti-apoptotic functions of NF-кB. IET Sys. Biol., 3 (2009), 356-367. [CrossRef] [Google Scholar]
  33. P. Ragazzini, G. Gamberi, M.S. Benassi, C. Orlando, R. Sestini, C. Ferrari, L. Molendini, M.R. Sollazzo, M. Merli, G. Magagnoli, F. Bertoni, T. Bohling, M. Pazzagli, P. Picci. Analysis of SAS gene and CDK4 and MDM2 proteins in low-grade osteosarcoma. Cancer Detection and Prevention, 23 (1999), 129-136. [CrossRef] [PubMed] [Google Scholar]
  34. D.R. Schrider, M.W. Hahn. Gene copy-number polymorphism in nature. Proc. Roy. Soc. B, 277 (2010), 3213-3221. [CrossRef] [Google Scholar]
  35. M.L. Smith, Y.R. Seo. p53 regulation of DNA excision repair pathways. Mutagenesis, 17 (2002), 149-156. [CrossRef] [PubMed] [Google Scholar]
  36. V. Stambolic, D. MacPherson, D. Sas, Y. Lin, B. Snow, Y. Jang, S. Benchimol, T.W. Mak. Regulation of PTEN transcription by p53. Mol. Cell, 8 (2001), 317-325. [Google Scholar]
  37. A.H. Stegh. Targeting the p53 signaling pathway in cancer therapy - the promises, challenges and perils. Expert Opinion on Therapeutic Targets, 16 (2012), 67-83. [CrossRef] [PubMed] [Google Scholar]
  38. J.M. Stommel, G.M. Wahl. A new twist in the feedback loop: stress-activated MDM2 destabilisation is required for p53 activation. Cell Cycle, 4 (2005), 411-417. [CrossRef] [PubMed] [Google Scholar]
  39. M. Sturrock, A.J. Terry, D.P. Xirodimas, A.M. Thompson, M.A.J. Chaplain. Spatio-temporal modelling of the Hes1 and p53-Mdm2 intracellular signalling pathways. J. Theor. Biol., 273 (2011), 15-31. [CrossRef] [PubMed] [Google Scholar]
  40. M. Sturrock, A.J. Terry, D.P. Xirodimas, A.M. Thompson, M.A.J. Chaplain. Influence of the nuclear membrane, active transport, and cell shape on the Hes1 and p53-Mdm2 pathways: insights from spatio-temporal modelling. B. Math. Biol., 74 (2012), 1531-1579. [CrossRef] [Google Scholar]
  41. A.J. Terry, M. Sturrock, J.K. Dale, M. Maroto, M.A.J. Chaplain. A spatio-temporal model of Notch signalling in the zebrafish segmentation clock: conditions for synchronised oscillatory dynamics. PLoS ONE, 6 (2011), e16980. [CrossRef] [PubMed] [Google Scholar]
  42. A.J. Terry, M.A.J. Chaplain. Spatio-temporal modelling of the NF-кB signalling pathway: The roles of diffusion, active transport, and cell geometry. J. Theor. Biol., 290 (2011), 7-26. [CrossRef] [PubMed] [Google Scholar]
  43. R. Weinberg. The Biology of Cancer. Garland Science: Taylor & Francis Group, 2007. [Google Scholar]
  44. D.P. Xirodimas, C.W. Stephen, D.P. Lane. Cocompartmentalization of p53 and Mdm2 is a major determinant for Mdm2-mediated degradation of p53. Experimental Cell Research, 270 (2001), 66-77. [CrossRef] [PubMed] [Google Scholar]
  45. T. Zhang, P. Brazhnik, J.J. Tyson. Exploring mechanisms of the DNA-damage response: p53 pulses and their possible relevance to apoptosis. Cell Cycle, 6 (2007), 85-94. [CrossRef] [PubMed] [Google Scholar]

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